Catalyst-free synthesis of diversely substituted 6H-benzo[c]chromenes and 6H-benzo[c]chromen-6-ones in aqueous media under MWI

Literature Information

Publication Date 2012-10-09
DOI 10.1039/C2GC36379H
Impact Factor 10.182
Authors

Yan He, Xinying Zhang, Liangyan Cui, Jianji Wang, Xuesen Fan


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Abstract

In this paper, a catalyst-free synthesis of diversely substituted 6H-benzo[c]chromenes and 6H-benzo[c]chromen-8-ols via cascade reactions of 2-(2-(allyloxy)phenyl)furan and 2-(2-(prop-2-ynyloxy)phenyl)furan, featured with intramolecular Diels–Alder reactions of furan with unactivated alkene/alkyne in aqueous media under MWI, was developed. In addition, an environmentally friendly oxidation of 6H-benzo[c]chromenes into the corresponding benzo[c]chromen-6-ones using aqueous H2O2 as an oxidant, in the absence of any activator/catalyst, was also revealed.

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