Protonreduction to hydrogen in biological and chemical systems
Literature Information
In the drive to devise catalytic systems to convert solar energy into the energy of chemical bonds, chemists and electrochemists are seeking inspiration from our understanding of enzymes involved in bioenergetics. This is particularly true for generating molecular hydrogen from high energy electrons derived from solar driven water splitting. In this case the natural enzymes are the [NiFe]- and [FeFe]-hydrogenases. In this article we review our present understanding of the structure and mechanistic functioning of these enzymes and how they are providing a blue print to the design and understanding of the mechanism of a variety of synthesized catalysts for proton reduction chemistry.
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Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.










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