A gram scale synthesis of a multi-13C-labelled anthocyanin, [6,8,10,3′,5′-13C5]cyanidin-3-glucoside, for use in oral tracer studies in humans

Literature Information

Publication Date 2011-09-05
DOI 10.1039/C1CC14323A
Impact Factor 6.222
Authors

Qingzhi Zhang, Nigel P. Botting, Colin Kay


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Abstract

The major dietary anthocyanin, cyanidin-3-glucoside, was prepared on a 4 g scale from three units of diethyl [2-13C]malonate and one unit of [1,3-13C2]acetone, such that five isotope locations were distributed throughout the molecule to provide a penta-13C5-labelled anthocyanin, [6,8,10,3′,5′-13C5]cyanidin-3-glucoside chloride, for use in human stable-isotope tracer studies.

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