Acyl hydrazides as peptoid sub-monomers
Literature Information
Publication Date
2011-09-05
DOI
10.1039/C1CC12750K
Impact Factor
6.222
Authors
Bani Kanta Sarma, Muhammed Yousufuddin, Thomas Kodadek
View Original
Abstract
The use of acyl hydrazides as peptoid sub-monomers is investigated. We demonstrate here that azapeptoids derived entirely from acyl hydrazides can be made conveniently and efficiently using standard peptoid sub-monomer chemistry. Structural studies reveal that the main chain amide bond in these molecules predominantly adopts a trans conformation. A high-quality one bead one compound library of tetramers was made by split and pool synthesis and we found that the identity of the molecule on a single bead could be determined by tandem MALDI mass spectrometry.
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Acta Materialia
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Source Journal
Chemical Communications
CiteScore:
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Recommended Compounds
![N,N'-1,2-Ethanediylbis[2-(vinylsulfonyl)acetamide] structure](https://static.chemtradehub.com/structs/667/66710-66-5-b556.webp "N,N'-1,2-Ethanediylbis[2-(vinylsulfonyl)acetamide] structure")
N,N'-1,2-Ethanediylbis[2-(vinylsulfonyl)acetamide]
CAS Number:
66710-66-5
Molecular Formula:
C10H16N2O6S2
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