A thiophen-thiooxorhodamine conjugate fluorescent probe for detecting mercury in aqueous media and living cells

Literature Information

Publication Date 2010-09-22
DOI 10.1039/C0OB00452A
Impact Factor 3.876
Authors

Yi Zhou, Xue-Yan You, Yuan Fang, Ju-Ying Li, Ke Liu, Cheng Yao


View Original

Abstract

A rhodamine-based sensor RB-S2 was designed and synthesized by combination of the thiospirolacton chromophore and the thiophen ring block with high affinity to Hg2+. Probe RB-S2 exhibits high selectivity and excellent sensitivity in both absorbance and fluorescence detection of Hg2+ in aqueous solution. In addition, fluorescent imaging of Hg2+ in MCF-7 cells is also successfully demonstrated.

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Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry
CiteScore: 3.4
Self-citation Rate: 10.3%
Articles per Year: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

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