Electrochemical impedance study of the interaction of metal ions with unlabeled PNA

Literature Information

Publication Date 2010-08-03
DOI 10.1039/C0CC00986E
Impact Factor 6.222
Authors

Lan Gao, Congjuan Li, Xiaohong Li, Heinz-Bernhard Kraatz


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Abstract

The interactions of the metal ions Mg2+, Zn2+, Ni2+, and Co2+ with thin films of peptide nucleic acids (PNAs) were studied by electrochemical impedance spectroscopy (EIS), and the results show that Zn2+, Ni2+ and Co2+ interacted favorably with the PNA film involving the backbone and the nucleobases with the exception of Mg2+ for which the interaction with the backbone appears to be dominant.

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