Stereoselective Ir(iii)-catalyzed dimerization reaction of enynes: an entry to functionalized polyunsaturated and cyclic systems
Literature Information
Mehdi Ez-Zoubir, Florent Le Boucher d'Herouville, Jack A. Brown, Virginie Ratovelomanana-Vidal, Véronique Michelet
The Ir(III) complex [Ir2H2I3((rac)-Binap)2]+I− efficiently promotes the selective dimerization of 1,6-, 1,7-enynes and functionalized alkynes. This catalytic process results in the formation of head-to-head isomers with (E)-stereoselectivity. Subsequent Rh-catalyzed cycloisomerization under reductive conditions led to the corresponding 1,2-dialkylidenecyclopentane derivatives.
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