The highly enantioselective Michael addition of ketones to nitrodienes catalyzed by the efficient organocatalyst system of pyrrolidinyl-thioimidazole and chiral thioureido acid
Literature Information
Zhao-Bo Li, Shu-Ping Luo, Yi Guo, Ai-Bao Xia, Dan-Qian Xu
The highly enantioselective Michael addition reaction of ketones to nitrodienes was promoted efficiently by the accessible and fine-tunable organocatalytic system of pyrrolidinyl-thioimidazole and chiral thioureido acid. The corresponding adducts were afforded in good yields with high diastereoselectivities (up to 99 : 1) and excellent enantioselectivities (up to 99% ee).
Recommended Journals

European Journal of Wood and Wood Products

Helvetica Chimica Acta

Pure and Applied Chemistry

Organic Preparations and Procedures International

Pharmacological Reviews

Planta Medica

Science Progress

Proceedings of the National Academy of Sciences of the United States of America

Israel Journal of Chemistry

Journal of Catalysis
Related Literature
Self-assembled bulk heterojunctions from integral molecules with nonconjugately linked donor and acceptor units for photovoltaic applications
Hao Liu, Huaizhi Gao, Jun Lin, Tasawar Hayat, Ahmed Alsaedi, Zhan'ao Tan
DOI: 10.1039/D0SE00206B
A thiophene bridged naphthalimide–porphyrin complex with enhanced activity and stability in photocatalytic H2 evolution
Govardhana Babu Bodedla, Geliang Tang, Jianzhang Zhao, Xunjin Zhu
DOI: 10.1039/D0SE00356E
A novel nonheme manganese(ii) complex for (electro) catalytic oxidation of water
Dattaprasad D. Narulkar, Anil Kumar U., Sunder N. Dhuri, Anil Kumar Vardhaman
DOI: 10.1039/D0SE00232A
EndoV/DNA ligase mutation scanning assay using microchip capillary electrophoresis and dual-color laser-induced fluorescence detection
Małgorzata A. Witek, John K. Osiri, Hong Wang, Rondedrick Sinville, Hanna Pincas, Francis Barany
DOI: 10.1039/C1AY05366C
Topical delivery of chemotherapeutic drugs using nano-hybrid hydrogels to inhibit post-surgical tumour recurrence
Chendan Liu, Yudi Ma, Song Guo, Bingfang He, Tianyue Jiang
DOI: 10.1039/D0BM01766C
A simple in-house dry ashing chamber for the rapid determination of total mercury in organic-rich solid materials by oxidative pyrolysis followed by CVAAS and FI-ICPMS detection
M. V. Balarama Krishna, A. C. Sahayam, D. Karunasagar
DOI: 10.1039/C1AY05624G
Influence of high-pressure torsion deformation on the corrosion behaviour of a bioresorbable Mg-based alloy studied by positron annihilation
Philipp Brunner, Florian Brumbauer, Eva-Maria Steyskal, Oliver Renk, Annelie-Martina Weinberg, Hartmuth Schroettner, Roland Würschum
DOI: 10.1039/D1BM00166C
You might also like
What industries use (1R,3S)-1,3-Cyclopentanediol (CAS: 16326-97-9)?
(1R,3S)-1,3-Cyclopentanediol finds applications in various industries. In the ph...
What precautions should be taken when handling N'-[4-(Dimethylamino)phenyl]-N,N-dimethyl-1,4-benzenediamine (CAS: 637-31-0)?
When handling N'-[4-(Dimethylamino)phenyl]-N,N-dimethyl-1,4-benzenediamine, it i...
Are there alternatives to 5-(2,4-Difluorophenyl)-2-methoxypyrimidine (CAS: 1352318-16-1) in synthesis?
There are several alternatives to 5-(2,4-Difluorophenyl)-2-methoxypyrimidine in ...
What regulatory guidelines apply to 1-(3-Methoxyphenoxy)propan-2-ol (CAS: 382141-68-6)?
1-(3-Methoxyphenoxy)propan-2-ol (CAS: 382141-68-6) must comply with the Globally...
Is Tetrodotoxin Citrate (CAS: 18660-81-6) safe?
Tetrodotoxin Citrate is extremely dangerous and should be handled with extreme c...
What are the main uses of 2-Methyl-2-propanyl [(1R,3S)-3-hydroxycyclopentyl]carbamate (CAS: 225641-84-9)?
2-Methyl-2-propanyl [(1R,3S)-3-hydroxycyclopentyl]carbamate (CAS: 225641-84-9) i...
How should waste containing 4-(2-Hydroxyhexafluoroisopropyl)Benzoic Acid (CAS: 16261-80-6) be handled?
Waste containing 4-(2-Hydroxyhexafluoroisopropyl)Benzoic Acid (CAS: 16261-80-6) ...
How is 2-Methyl-2-proanyl {(2S)-1-[(benzyloxy)amino]-3-hydroxy-3-methyl-1-oxo-2-butanyl}carbamate (CAS: 102507-19-7) typically synthesized?
2-Methyl-2-proanyl {(2S)-1-[(benzyloxy)amino]-3-hydroxy-3-methyl-1-oxo-2-butanyl...
What is Benzeneethanamine, α-ethyl-, hydrochloride (1:1) (CAS: 20735-15-3)?
Benzeneethanamine, α-ethyl-, hydrochloride (1:1) is an organic compound with the...
Are there alternatives to 3-{(E)-[4-(Dimethylamino)phenyl]diazenyl}benzoic acid (CAS: 20691-84-3) in synthesis?
In the synthesis of compounds similar to 3-{(E)-[4-(Dimethylamino)phenyl]diazeny...
Source Journal
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.




