Measurement of hetero-nuclear distances using a symmetry-based pulse sequence in solid-state NMR

Literature Information

Publication Date 2010-06-24
DOI 10.1039/B926546E
Impact Factor 3.676
Authors

Lei Chen, Olivier Lafon, Julien Trébosc, Feng Deng, Jean-Paul Amoureux


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Abstract

A Symmetry-based Resonance-Echo DOuble-Resonance (S-REDOR) method is proposed for measuring hetero-nuclear dipolar couplings between two different spin-1/2 nuclei, under fast magic-angle spinning. The hetero-nuclear dipolar couplings are restored by employing the SR421 sequence, which requires the rf-field strength to be only twice the spinning frequency. The S-REDOR experiment is extended to S-RESPDOR (Symmetry-based Resonance-Echo Saturation-Pulse DOuble-Resonance) for determining dipolar coupling between a spin-1/2 nucleus (e.g.13C) and 14N. It is demonstrated that S-REDOR and S-RESPDOR methods suppress efficiently the homo-nuclear dipolar interaction of the irradiated nucleus and benefit from high robustness to the rf-field inhomogeneity, chemical shielding and dipolar truncation. Therefore, these methods allow the measurement of 13C/14,15N distances, with 13C observation, in uniformly 13C-labeled samples. Furthermore, we provide analytical solutions for the S-REDOR and S-RESPDOR dephasing curves. These solutions facilitate the measurement of hetero-nuclear distances from experimental data.

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DOI: 10.1039/C8CP90059K

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Source Journal

Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics
CiteScore: 5.5
Self-citation Rate: 10.3%
Articles per Year: 3036

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.

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