An ultrasensitive electrochemical “turn-on” label-free biosensor for Hg2+with AuNP-functionalized reporter DNA as a signal amplifier

Literature Information

Publication Date 2009-08-05
DOI 10.1039/B911163H
Impact Factor 6.222
Authors

Rong-Mei Kong, Xiao-Bing Zhang, Liang-Liang Zhang, Xiao-Yong Jin, Shuang-Yan Huan, Guo-Li Shen, Ru-Qin Yu


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Abstract

A highly selective electrochemical biosensor for the ultrasensitive detection of Hg2+ in aqueous solution has been developed based on the strong and specific binding of Hg2+ by two DNAthymine bases (T–Hg2+–T) and the use of AuNP-functionalized reporter DNA to achieve signal amplification.

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