Detection of single-nucleotide mismatches using scanning electrochemical microscopy

Literature Information

Publication Date 2009-01-05
DOI 10.1039/B819876D
Impact Factor 6.222
Authors

Piotr Michal Diakowski, Heinz-Bernhard Kraatz


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Abstract

Probing ds-DNA films in the presence of Zn2+ ions by scanning electrochemical microscopy (SECM) allows the unequivocal detection of a single-nucleotide mismatch and provides information about its position within the duplex.

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