Amphiphilic nanoassemblies for the detection of peptides and proteins using fluorescence and mass spectrometry
Literature Information
Publication Date
2009-03-10
DOI
10.1039/B818484D
Impact Factor
4.616
Authors
Malar A. Azagarsamy, Andrea Gomez-Escudero, Volkan Yesilyurt, Richard W. Vachet, S. Thayumanavan
View Original
Abstract
Amphiphilic nanostructures provide unique environments for molecules that are incompatible with the solvent to be sequestered within their interior. These internal environments provide opportunities for concentrating an analyte or transducer molecule for detection, and the functional groups within the amphiphiles provide an opportunity for incorporating specificity or selectivity toward analytes. In this review, we discuss ways in which amphiphilic assemblies can be used to detect peptides and proteins with a particular emphasis on facially amphiphilic polymers and dendrimers.
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Analyst
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Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
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