Isolation, structure and fatty acid synthesis inhibitory activities of platensimycin B1–B3 from Streptomyces platensis

Literature Information

Publication Date 2008-09-05
DOI 10.1039/B810113B
Impact Factor 6.222
Authors

Chaowei Zhang, John Ondeyka, Deborah L. Zink, Bruce Burgess, Jun Wang, Sheo B. Singh


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Abstract

Platensimycin B1–B3 are natural congeners of platensimycin with modest to significant changes in the benzoic acid portion of the molecule, leading to attenuation in the biological activities and thus confirming the significance of the free carboxylate for the potent activity.

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