Copper-catalyzed asymmetric allylic substitution with aryl and ethylGrignard reagents

Literature Information

Publication Date 2008-09-09
DOI 10.1039/B809140D
Impact Factor 6.222
Authors

Khalid B. Selim, Ken-ichi Yamada, Kiyoshi Tomioka


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Abstract

Phenyl- and ethyl-magnesium bromides undergo regioselective asymmetric allylic substitution with high enantioselectivity under the catalysis of chiral amidophosphane–copper(I) complexes.

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