Oxidative decarboxylative synthesis of 2-H-imidazolines from glyoxylic acid and 1,2-diamines
Literature Information
Kenichi Murai, Maiko Morishita, Ryo Nakatani, Hiromichi Fujioka, Yasuyuki Kita
A novel method to prepare 2-H-imidazolines from glyoxylic acid monohydrate and 1,2-diamines is described; the key reaction of this method is the oxidative decarboxylation of the 2-carboxy imidazolidines by NBS.
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![1,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl]-3,5-pyrazolidinedione structure 1,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl]-3,5-pyrazolidinedione structure](https://static.chemtradehub.com/structs/57-/57-96-5-efcc.webp)



