Activation of organozinc reagents with t-Bu-P4 base for transition metal-free catalytic SN2′ reaction
Literature Information
Koji Kobayashi, Masahiro Ueno, Hiroshi Naka, Yoshinori Kondo
The t-Bu-P4 base was found to be an excellent catalyst for activating organozinc reagents and was used to promote the SN2′ reaction of α,β-unsaturated esters bearing a γ-chloride using various organozinc reagents: these reactions proceeded in high yields with excellent chemo-and regioselectivity.
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