Towards quantitatively reproducible substrates for SERS

Literature Information

Publication Date 2008-07-25
DOI 10.1039/B800340H
Impact Factor 4.616
Authors

Roger M. Jarvis, Helen E. Johnson, Emma Olembe, Arunkumar Panneerselvam, Mohammad A. Malik, Mohammad Afzaal, Paul O'Brien, Royston Goodacre


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Abstract

There is a need for a method to facilitate the development of novel, reproducible colloidal surface-enhanced Raman scattering (SERS) substrates to encourage the use of SERS in applied studies. In this study we show for the first time that by using suitably designed SERS experiments in conjunction with multivariate analysis of variance (MANOVA), an objective assessment of colloidal SERS reproducibility can be made. This is demonstrated with the analyte cresyl violet, but could be extended to any analyte of interest for which reproducible SERS data are needed.

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