Electrokinetic probes for single-step screening of polyol stereoisomers: the virtues of ternary boronate ester complex formation

Literature Information

Publication Date 2007-10-26
DOI 10.1039/B714215C
Impact Factor 6.222
Authors

Claire Kaiser, Giselle Segui-Lines, Jason C. D'Amaral, Adam S. Ptolemy, Philip Britz-McKibbin


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Abstract

Electrokinetic probes based on the differential migration of ternary boronate ester complexes permit the selective analysis of micromolar levels of UV-transparent polyol stereoisomers in urine samples via dynamic complexation–capillary electrophoresis that is applicable to single-step screening of in-born errors of sugarmetabolism, such as galactosemia.

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