(2S,4R)-4-(3-Bromobenzyl)pyrrolidine-2-carboxylic acid hydrochloride
CAS Number:
1049734-10-2
Molecular Formula:
C12H15BrClNO2
An in situ amperometric biosensor for the detection of vapours from explosive compounds
Literature Information
Publication Date
2007-11-30
DOI
10.1039/B713269G
Impact Factor
4.616
Authors
Christopher David Gwenin, Maher Kalaji, Catharine Melanie Kay, Peter Anthony Williams, Duarte Novaes Tito
View Original
Abstract
An amperometric biosensor based on genetically-modified enzymes was used for the in situdetection of trace vapours from a number of explosive compounds. The vapour samples that were generated from a purpose-built vapour generator were collected and pre-concentrated using a trap able to concentrate samples at a rate of 60-fold per minute of sampling. The amperometric biosensor achieved a remarkably low vapour detection limit of 6 parts per trillion from a room temperature sample. The specific activity of the reported enzyme toward a number of explosive compounds was also confirmed using absorbance measurements.
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