Activity-based fluorescent reporters for monoamine oxidases in living cells
Literature Information
Aaron E. Albers, Katherine A. Rawls, Christopher J. Chang
Monoamine Oxidase Reporters 1 and 2 (MR1 and MR2) are substrate-tethered activity probes that utilize a tandem amine oxidation/β-elimination mechanism to detect MAO chemistry in vitro and in living cells directly and specifically without the need for additional enzymes or other activating reagents.
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