Colorimetric Cu2+ detection with a ligation DNAzyme and nanoparticles

Literature Information

Publication Date 2007-10-24
DOI 10.1039/B712421J
Impact Factor 6.222
Authors

Juewen Liu, Yi Lu


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Abstract

Using a Cu2+-dependent DNA ligation DNAzyme, a colorimetric sensor for Cu2+ has been developed based on directed assembly of DNA-functionalized gold nanoparticles by the ligation product, and such ligation DNAzyme-based sensors are intrinsically more sensitive than cleavage DNAzyme systems due to the lack of background.

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