Rescue of the streptomycin antibiotic activity by using streptidine as a “decoy acceptor” for the aminoglycoside-inactivating enzyme adenyl transferase

Literature Information

Publication Date 2007-06-13
DOI 10.1039/B704785A
Impact Factor 6.222
Authors

Montserrat Latorre, Pablo Peñalver, Julia Revuelta, Juan Luis Asensio, Eduardo García-Junceda, Agatha Bastida


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Abstract

The use of streptidine as a “decoy acceptor” allows the antibiotic activity of streptomycin to recover against the Escherichia coli strain overexpressing the aminoglycoside-modifying enzyme 6-O-adenyl transferase.

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