Synthesis and reactivity of [18F]-N-fluorobenzenesulfonimide
Literature Information
Harriet Teare, Edward G. Robins, Erik Årstad, Sajinder K. Luthra, Véronique Gouverneur
A novel [18F]NF reagent and two novel radiochemical transformations have been developed: [18F]NFSi has been prepared from sodium dibenzenesulfonimide and reacted in the presence of silyl enol ethers and allylsilanes to deliver labelled fluorinated ketones and allylic fluorides respectively; the radiosynthesis of the fluorinated A ring of vitamin D3 has also been completed with success.
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