Chemoselective derivatization of a bionanoparticle by click reaction and ATRP reaction
Literature Information
Qingbing Zeng, Tao Li, Brandon Cash, Siqi Li, Fang Xie, Qian Wang
Horse spleen apoferritin, the hollow protein shell derived from ferritin, a special biological nanoparticle, can be chemoselectively modified at the lysine residues, which affords a robust scaffold for further chemical reactions including Cu(I)-catalyzed azide–alkyne cycloaddition reaction and atom transfer radical polymerization reaction.
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