Total synthesis of buergerinin F via effective construction of the asymmetric quaternary carbons using an enantioselective aldol reaction

Literature Information

Publication Date 2005-07-14
DOI 10.1039/B507401K
Impact Factor 6.222
Authors

Isamu Shiina, Yo-ichi Kawakita, Ryoutarou Ibuka, Kazutoshi Yokoyama, Yu-suke Yamai


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Abstract

An efficient method for the synthesis of (+)-buergerinin F is established via the enantioselective aldol reaction of a tetrasubstituted ketene silyl acetal with crotonaldehyde, followed by intramolecular Wacker-type ketalization.

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