Novel Pd(ii)-catalysed N,O-bicyclisation as an efficient route to the 6-oxa-2-azabicyclo[3.2.1]octane skeleton

Literature Information

Publication Date 2005-07-04
DOI 10.1039/B506731F
Impact Factor 6.222
Authors

Peter Szolcsányi, Tibor Gracza


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Abstract

1-(Benzyloxycarbonylamino)-hex-5-en-3-ol (5) undergoes a novel Pd(II)/CuCl2-catalysed bicyclisation to furnish the corresponding 6-oxa-2-azabicyclo[3.2.1]octane (6) in good yield.

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