2,2-Dimethyl cyclopentanones by acid catalyzed ring expansion of isopropenylcyclobutanols. A short synthesis of (±)-α-cuparenone and (±)-herbertene
Literature Information
Angela M. Bernard, Angelo Frongia, Francesco Secci, Pier P. Piras
2,2-Dimethyl cyclopentanones are readily prepared by acid catalyzed ring expansion of isopropenylcyclobutanols; the method allows ready access to the family of sesquiterpenes cuparanes and herbertanes, as demonstrated by the synthesis of (±)-α-cuparenone and the direct precursor of (±)-herbertene.
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