Highly regio-, chemo- and diastereoselective synthesis of oxa-bridged spirocycles: A novel observation of reverse selectivity

Literature Information

Publication Date 2005-06-21
DOI 10.1039/B504692K
Impact Factor 6.222
Authors

Sengodagounder Muthusamy, Janagiraman Krishnamurthi, Munirathnam Nethaji


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Abstract

The reverse regio- and diastereoselectivities are observed between the reactions involving 5- and 6-membered-ring cyclic carbonyl ylide dipoles with α-methylene ketones. A mild catalytic route to synthesize spirocyclic systems with high regio-, chemo- and diastereoselectivities is described.

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