gem-Difluorination of 2,2-diaryl-1,3-dithiolanes by Selectfluor® and pyridinium polyhydrogen fluoride
Literature Information
V. Prakash Reddy, Ramesh Alleti, Meher K. Perambuduru, Urs Welz-Biermann, Herwig Buchholz, G. K. Surya Prakash
2,2-Diaryl-1,3-dithiolanes, readily obtainable from diaryl ketones, were transformed into the corresponding gem-difluoro compounds using a novel reagent combination involving Selectfluor速 and pyridinium polyhydrogen fluoride (PPHF) under mild conditions in moderate to good yields.
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