gem-Difluorination of 2,2-diaryl-1,3-dithiolanes by Selectfluor® and pyridinium polyhydrogen fluoride

Literature Information

Publication Date 2004-12-08
DOI 10.1039/B414254C
Impact Factor 6.222
Authors

V. Prakash Reddy, Ramesh Alleti, Meher K. Perambuduru, Urs Welz-Biermann, Herwig Buchholz, G. K. Surya Prakash


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Abstract

2,2-Diaryl-1,3-dithiolanes, readily obtainable from diaryl ketones, were transformed into the corresponding gem-difluoro compounds using a novel reagent combination involving Selectfluor速 and pyridinium polyhydrogen fluoride (PPHF) under mild conditions in moderate to good yields.

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Contents and Chemical Biology

Front/Back Matter

DOI: 10.1039/B805399P

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Chemical Communications

Chemical Communications
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