Nitrile oxide cycloadditions in supercritical carbon dioxide
Literature Information
Connie K. Y. Lee, Andrew B. Holmes, Bushra Al-Duri, Gary A. Leeke, Regina C. D. Santos, Jonathan P. K. Seville
The regioselectivity of dipolar cycloadditions of mesitonitrile oxide to various dipolarophiles in supercritical carbon dioxide can be tuned by changes in density, the magnesium bromide-mediated cycloaddition to pent-1-en-3-ol proceeding with higher stereoselectivity than in most conventional solvents.
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