Nitrile oxide cycloadditions in supercritical carbon dioxide

Literature Information

Publication Date 2004-10-05
DOI 10.1039/B411561A
Impact Factor 6.222
Authors

Connie K. Y. Lee, Andrew B. Holmes, Bushra Al-Duri, Gary A. Leeke, Regina C. D. Santos, Jonathan P. K. Seville


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Abstract

The regioselectivity of dipolar cycloadditions of mesitonitrile oxide to various dipolarophiles in supercritical carbon dioxide can be tuned by changes in density, the magnesium bromide-mediated cycloaddition to pent-1-en-3-ol proceeding with higher stereoselectivity than in most conventional solvents.

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