Continuous two-dimensional field-flow fractionation: a novel technique for continuous separation and collection of macromolecules and particles
Literature Information
Publication Date
2005-02-16
DOI
10.1039/B410046H
Impact Factor
4.616
Authors
Pertti Vastamäki, Matti Jussila, Marja-Liisa Riekkola
View Original
Abstract
Instrumental techniques to analyse macromolecular and particulate materials have undergone rapid development in response to the need for high resolution, precise identification and characterization, and enrichment and collection for further analysis. Continuous two-dimensional field-flow fractionation (2D-FFF), which is described in this article, is a novel technique for separation and collection of macromolecules and particles. 2D-FFF is based on the conventional field-flow fractionation principle but with carrier flow in two-dimensions. This overview discusses the principle of the technique, describes the instrumentation and suggests potential applications and further extensions. An overview of the basic field-flow fractionation principle is presented.
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