Construction of building-blocks for polyether synthesis using sequential catalytic ring-closing enyne and cross metathesis

Literature Information

Publication Date 2004-09-24
DOI 10.1039/B409067E
Impact Factor 6.222
Authors

J. Stephen Clark, Frédéric Elustondo, Marc C. Kimber


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Abstract

Highly functionalised six- and seven-membered cyclic ethers bearing a variety of side chains have been synthesised using ring-closing enyne metathesis and subsequent cross metathesis of the intermediate diene; one-pot enyne and cross metathesis has also been accomplished, allowing ring construction and side chain introduction to be performed in a single operation.

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Chemical Communications

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