Design of a robust Ru(salen) complex: aziridination with improved turnover number using N-arylsulfonyl azides as precursors

Literature Information

Publication Date 2004-08-13
DOI 10.1039/B407693A
Impact Factor 6.222
Authors

Kazufumi Omura, Tatsuya Uchida, Ryo Irie, Tsutomu Katsuki


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Abstract

A new robust fluorinated (OC)Ru(salen) complex was designed on the basis of an X-ray structure of its parent complex to show improved turnover numbers (up to 878) and enantioselectivities (up to 99%) in aziridination reactions using p-toluenesulfonyl (Ts) or p-nitrobenzenesulfonyl (Ns) azide as the nitrene precursor; the latter is synthetically advantageous since the Ns group is N-protecting and can be removed under mild conditions.

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