Zinc–proline catalyzed pathway for the formation of sugars

Literature Information

Publication Date 2004-05-27
DOI 10.1039/B404465G
Impact Factor 6.222
Authors

Jacob Kofoed, Miguel Machuqueiro, Jean-Louis Reymond, Tamis Darbre


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Abstract

Zn–proline catalyzes the aldolisation of unprotected glycolaldehyde in water to give tetroses and hexoses; threose (33% of the product mixture) was formed with 10% enantiomeric excess of the D-isomer.

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