Unprecedented copper-catalyzed asymmetric conjugate addition of organometallic reagents to α,β-unsaturated lactams
Literature Information
Mauro Pineschi, Federica Del Moro, Adriaan J. Minnaard, Ben L. Feringa
For the first time, an excellent enantioselectivity has been obtained in the conjugate addition of hard organometallic reagents to α,β-unsaturated lactams bearing appropriate protecting–activating groups on the nitrogen.
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