Facile palladium-catalysed synthesis of 1-aryl-1H-indazoles from 2-bromobenzaldehydes and arylhydrazines
Literature Information
Chan Sik Cho, Dong Kwon Lim, Nam Ho Heo, Tae-Jeong Kim, Sang Chul Shim
2-Bromobenzaldehydes react with arylhydrazines in toluene at 100 °C in the presence of a catalytic amount of a palladium catalyst and phosphorus chelating ligands such as 1,1′-bis(diphenylphosphino)ferrocene and 1,3-bis(diphenylphosphino)propane along with NaO-t-Bu to afford 1-aryl-1H-indazoles in good yields.
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