A simple copper salt catalysed the coupling of imidazole with arylboronic acids in protic solvent
Literature Information
Jing-Bo Lan, Li Chen, Xiao-Qi Yu, Jing-Song You, Ru-Gang Xie
In the presence of a catalytic amount of a simple copper salt, the coupling of imidazole with arylboronic acids was performed in methanol to give corresponding N-arylimidazoles in almost quantitative yields; this coupling reaction could also be performed in aqueous solutions to give N-arylimidazoles in excellent yields.
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