A simple copper salt catalysed the coupling of imidazole with arylboronic acids in protic solvent

Literature Information

Publication Date 2003-11-25
DOI 10.1039/B307734A
Impact Factor 6.222
Authors

Jing-Bo Lan, Li Chen, Xiao-Qi Yu, Jing-Song You, Ru-Gang Xie


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Abstract

In the presence of a catalytic amount of a simple copper salt, the coupling of imidazole with arylboronic acids was performed in methanol to give corresponding N-arylimidazoles in almost quantitative yields; this coupling reaction could also be performed in aqueous solutions to give N-arylimidazoles in excellent yields.

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