Enantio-differentiating catalytic oxidation by a biomimetic trinuclear copper complex containing l-histidine residues

Literature Information

Publication Date 2003-07-28
DOI 10.1039/B307349A
Impact Factor 6.222
Authors

Laura Santagostini, Michele Gullotti, Roberto Pagliarin, Enrico Monzani, Luigi Casella


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Abstract

The trinuclear complex [Cu3PHI]6+, derived from a ligand containing two chiral L-histidine residues, performs the catalytic oxidation of L- and D-Dopa with remarkable enantio-differentiation; this depends on the anchoring effect provided by the copper center which is not participating in the catalytic reaction and recognizes the chirality of the substrate.

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