Highly stereoselective, thermodynamically controlled and reversible formation of a new P-chiral phosphine

Literature Information

Publication Date 2003-07-31
DOI 10.1039/B306153A
Impact Factor 6.222
Authors

Igor V. Komarov, Anke Spannenberg, Jens Holz


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Abstract

The highly stereoselective formation of a chiral α-hydroxyphospholane under very mild condition is reported, taking place on a camphor skeleton by an intramolecular thermodynamically controlled and reversible addition of an epimeric secondary phosphine group to a carbonyl group.

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