Synthesis of a model DEF-ring core of hexacyclinic acid
Literature Information
Paul A. Clarke, Matthew Grist, Mark Ebden, Claire Wilson
The first synthesis of a DEF-ring system of hexacyclinic acid is reported. The key steps being an intramolecular Pd(0) π-allyl substitution reaction, followed by a transannular iodocyclisation with acetyl hypoiodite.
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Chemical Communications

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