Synthesis of a model DEF-ring core of hexacyclinic acid

Literature Information

Publication Date 2003-06-03
DOI 10.1039/B303706A
Impact Factor 6.222
Authors

Paul A. Clarke, Matthew Grist, Mark Ebden, Claire Wilson


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Abstract

The first synthesis of a DEF-ring system of hexacyclinic acid is reported. The key steps being an intramolecular Pd(0) π-allyl substitution reaction, followed by a transannular iodocyclisation with acetyl hypoiodite.

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Chemical Communications

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