Palladium catalysed [2 + 2 + 1] intramolecular cycloaddition for the preparation of bicyclo[3.3.0]octa-1.5-dien-3-ones from 1,6-diynes

Literature Information

Publication Date 2003-06-24
DOI 10.1039/B302841K
Impact Factor 6.222
Authors

Ronald Grigg, Lixin Zhang, Simon Collard, Ann Keep


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Abstract

Palladium catalysed [2 + 2 + 1] cycloaddition of 1,6-heptadiynes with CO (1 atm) furnishes bicyclo[3.3.0]octa-1,5-dien-3-ones in 30–74% yield.

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