Synthesis of a hyaluronan neoglycopolymer by ring-opening metathesis polymerization

Literature Information

Publication Date 2003-05-30
DOI 10.1039/B301734F
Impact Factor 6.222
Authors

Suri Iyer, Shyam Rele, Gabriela Grasa, Steven Nolan


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Abstract

A hyaluronan (HA)-derived disaccharide was synthesized bearing an n-pentenyl spacer arm, which facilitated disaccharide derivatization with a norbornene template. Subsequent ring opening metathesis polymerization of the monomer produced an HA-mimetic neoglycopolymer of low polydispersity.

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