A novel concept to activate enediynes for DNA cleavage
Literature Information
Michael Schmittel, Giampietro Viola, Francesco Dall’Acqua, Guido Morbach
A novel concept is presented to activate enediynes via a biscumulenic intermediate using photoinduced electron transfer (PET).
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![N-[4-(Cyanoethynyl)phenyl]-16-oxo-4,7,10,13-tetraoxa-17-azahenicos-1-yn-21-amide structure N-[4-(Cyanoethynyl)phenyl]-16-oxo-4,7,10,13-tetraoxa-17-azahenicos-1-yn-21-amide structure](https://static.chemtradehub.com/structs/218/2183440-36-8-68cb.webp)