Mk-2461 | CAS No. 917879-39-1

Mk-2461

Basic Information

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CAS Number

917879-39-1

Molecular Formula

C24H25N5O5S

Molecular Weight

495.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

732.4°C at 760 mmHg

SMILES

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CN1C=C(C=N1)C2=CC3=C(C=CC4=C(C3=O)C=C(C=C4)NS(=O)(=O)N(C)CC5COCCO5)N=C2

InChI

InChI=1S/C24H25N5O5S/c1-28-13-18(12-26-28)17-9-22-23(25-11-17)6-4-16-3-5-19(10-21(16)24(22)30)27-35(31,32)29(2)14-20-15-33-7-8-34-20/h3-6,9-13,20,27H,7-8,14-15H2,1-2H3/t20-/m1/s1

InChIKey

JGEBLDKNWBUGRZ-HXUWFJFHSA-N

LogP

2.1525999999999996

Topological Polar Surface Area

115.64999999999999 Å²

Hydrogen Bond Donor/Acceptor

1 / 10

Complexity

895

Safety Information

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Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

MK-2461
9-[[[(2R)-1,4-dioxan-2-yl]methyl-methylsulfamoyl]amino]-2-(1-methylpyrazol-4-yl)-11-oxobenzo[1,2]cyclohepta[2,4-b]pyridine
Mk-2461 .
Sulfamide, N-[(2R)-1,4-dioxan-2-ylmethyl]-N-methyl-N'-[3 -(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-
MK 2461
Sulfamide,N-((2R)-1,4-dioxan-2-ylmethyl)-N-methyl-N'-(3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo(4,5)cyclohepta(1,2-b)pyridin-7-yl)
UNII-4200RD53XF
N-[(2R)-1,4-Dioxan-2-ylmethyl]-N-methyl-N′-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]sulfamide (ACI)
N-((2R)-1,4-Dioxan-2-ylmethyl)-N-methyl-N′-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]sulfamide
CHEMBL1822792
AC-32072
NSC-800795
N-[(2R)-1,4-dioxan-2-ylmethyl]-N-methyl-N'-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]sulfuric diamide
SW219905-1
Sulfamide, N-((2R)-1,4-dioxan-2-ylmethyl)-N-methyl-N'-(3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo(4,5)cyclohepta(1,2-b)pyridin-7-yl)-
CHEBI:230540
CHEMBL1802916
N-[(2R)-1,4-dioxan-2-ylmethyl]-N-methyl-N'-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]sulfamide
s2774
CS-5537
14-[[[(2R)-1,4-dioxan-2-yl]methyl-methylsulfamoyl]amino]-5-(1-methylpyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
HY-50703
NCGC00346695-02
4200RD53XF
N-[(2R)-1,4-dioxan-2-ylmethyl]-N-methyl{[5-(1-methylpyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.0(3),?]pentadeca-1(15),3,5,7,9,11,13-heptaen-14-yl]amino}sulfonamide
MK2461
BRD-K56405753-001-02-4
Q27086785
F85378
BDBM50347659
NCGC00346695-05

MDL Number

MFCD11977739

FAQ

What are the physical and chemical properties of Mk-2461 (CAS: 917879-39-1)?

Mk-2461 is a crystalline solid with a high molecular weight. It has low water solubility but good solubility in organic solvents. Chemically, it is relatively stable under normal conditions but can react with strong oxidizers. Its reactivity is low in neutral and basic environments but increases in acidic conditions.

How is Mk-2461 (CAS: 917879-39-1) typically synthesized?

Mk-2461 is synthesized via a multi-step process involving the condensation of two aromatic molecules followed by amination. Common catalysts include palladium-based compounds, and the process typically yields about 85% to 90% purity. Selectivity is high, ensuring a pure product.

What industries use Mk-2461 (CAS: 917879-39-1)?

Mk-2461 is primarily used in the pharmaceutical industry for developing new drug candidates. It also finds applications in the polymer industry for synthesizing novel materials and in the semiconductor industry for creating advanced sensor devices.

What precautions should be taken when handling Mk-2461 (CAS: 917879-39-1)?

When handling Mk-2461, always wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Store it in a cool, dry place, away from oxidizers. In case of spill, use a fume hood and follow the safety data sheet (SDS) guidelines for proper disposal.