Piperaquine tetraphosphate tetrahydrate

Basic Information

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CAS Number

915967-82-7

Molecular Formula

C29H52Cl2N6O20P4

Molecular Weight

999.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Insecticides

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Solubility

H2O: ≥10mg/mL

SMILES

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C1CN(CCN1CCCN2CCN(CC2)C3=C4C=CC(=CC4=NC=C3)Cl)C5=C6C=CC(=CC6=NC=C5)Cl.O.O.O.O.OP(=O)(O)O.OP(=O)(O)O.OP(=O)(O)O.OP(=O)(O)O

InChI

InChI=1S/C29H32Cl2N6.4H3O4P.4H2O/c30-22-2-4-24-26(20-22)32-8-6-28(24)36-16-12-34(13-17-36)10-1-11-35-14-18-37(19-15-35)29-7-9-33-27-21-23(31)3-5-25(27)29;4*1-5(2,3)4;;;;/h2-9,20-21H,1,10-19H2;4*(H3,1,2,3,4);4*1H2

InChIKey

AMCQDGFOKTXHSY-UHFFFAOYSA-N

LogP

-1.5890999999999993

Topological Polar Surface Area

475.78 Å²

Hydrogen Bond Donor/Acceptor

20 / 26

Complexity

704

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Hygroscopic

Synonyms & References

English

Piperaquine tetraphosphate tetrahydrate
7-chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline,phosphoric acid,tetrahydrate
7-Chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline
Piperaquine phosphate
UNII-854D7K8LXB
Tox21_500235
Piperaquine Phosphate,(S)
AS-13305
E79008
Piperaquine tetraphosphate tetrahydrate, >=98% (HPLC)
Q27269589
PIPERAQUINE TETRAPHOSPHATE [EMA EPAR]
TETRAKIS(PHOSPHORIC ACID) PIPERAQUINE TETRAHYDRATE
915967-82-7
PIPERAQUINE PHOSPHATE [MART.]
DA-66739
Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro-, phosphate, hydrate (1:4:4)
854D7K8LXB
PIPERAQUINE PHOSPHATE [WHO-DD]
Piperaquine tetraphosphate hydrate
MFCD11870901
piperaquine phosphate tetrahydrate
DTXSID60238640
7-chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline;phosphoric acid;tetrahydrate
EURARTESIM COMPONENT PIPERAQUINE TETRAPHOSPHATE
AKOS027321718
NCGC00260920-01
HMS3260P11
1,3-Bis(4-(7-chloroquinolin-4-yl)piperazin-1-yl)propane tetrakis(phosphate) tetrahydrate
Piperaquine phosphate hydrate

MDL Number

MFCD11870901

FAQ

What is Piperaquine tetraphosphate tetrahydrate (CAS: 915967-82-7)?

Piperaquine tetraphosphate tetrahydrate is an anti-malarial drug with the CAS number 915967-82-7. It is a salt form of piperaquine, which is used in combination with other antimalarial agents to treat and prevent malaria. The compound has a chemical formula of C21H24N4O8P4·4H2O and is known for its stability and long-lasting efficacy against malaria parasites.

What are the main uses of Piperaquine tetraphosphate tetrahydrate (CAS: 915967-82-7)?

Piperaquine tetraphosphate tetrahydrate is primarily used in the treatment and prevention of malaria, especially in combination with other antimalarial drugs. It is also used in clinical trials and research to study its antiparasitic effects and to develop new antimalarial strategies.

Is Piperaquine tetraphosphate tetrahydrate (CAS: 915967-82-7) safe?

Piperaquine tetraphosphate tetrahydrate is generally considered safe when used as directed, but like any medication, it can have side effects. Common side effects include nausea, vomiting, and dizziness. Users should follow safety precautions, such as consulting a healthcare provider before use and avoiding the drug if you have known allergies or other health conditions.

How should Piperaquine tetraphosphate tetrahydrate (CAS: 915967-82-7) be stored?

Piperaquine tetraphosphate tetrahydrate should be stored in a cool, dry place away from direct sunlight and moisture. It should be kept in a tightly closed container to prevent degradation. The recommended storage temperature is between 15-30°C (59-86°F). Avoid storing it in extremes of temperature and humidity to ensure its stability and effectiveness.