(1-methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol

Basic Information

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CAS Number

912761-33-2

Molecular Formula

C10H17N3O

Molecular Weight

195.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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CN1C=CN=C1C(C2CCNCC2)O

InChI

InChI=1S/C10H17N3O/c1-13-7-6-12-10(13)9(14)8-2-4-11-5-3-8/h6-9,11,14H,2-5H2,1H3

InChIKey

BJMLIKMTFQKDFH-UHFFFAOYSA-N

LogP

0.4530999999999999

Topological Polar Surface Area

50.08 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

182

Synonyms & References

English

(1-Methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol
(1-Methyl-1H-imidazol-2-yl)(4-piperidinyl)methanol
α-(1-Methyl-1H-imidazol-2-yl)-4-piperidinemethanol (ACI)
(1-methylimidazol-2-yl)-piperidin-4-ylmethanol
MFCD08669772
EN300-113084
CHEMBL4537481
DB-013711
CS-0084127
CS-16011
Z1198180686
AKOS006228319
(1-methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol
912761-33-2
F52073

MDL Number

MFCD08669772

FAQ

What are the physical and chemical properties of (1-methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol (CAS: 912761-33-2)?

The compound (1-methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol has a crystalline form and a molecular weight of approximately 247.36 g/mol. It is poorly soluble in water but soluble in organic solvents. It exhibits moderate reactivity, particularly towards nucleophiles and bases. The compound is stable under normal conditions but should be stored in a dry, well-ventilated area.

How is (1-methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol (CAS: 912761-33-2) typically synthesized?

Synthesis of (1-methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol can be achieved through a multistep process involving the condensation of 1-methylimidazole with piperidine, followed by methylation. The reaction typically requires the use of a catalytic amount of a base like sodium hydride to promote the reaction. The yield can be optimized by careful control of reaction conditions and use of appropriate solvents.

What industries use (1-methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol (CAS: 912761-33-2)?

(1-methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol is primarily used in the pharmaceutical industry as a precursor in the synthesis of drugs. It also has applications in polymer chemistry, where it acts as a crosslinking agent, and in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling (1-methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol (CAS: 912761-33-2)?

When handling (1-methyl-1H-imidazol-2-yl)(piperidin-4-yl)methanol, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat to protect against skin and eye contact. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.