4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1)

Basic Information

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CAS Number

895519-91-2

Molecular Formula

C30H33F3N8O4S

Molecular Weight

658.71 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC1=C(C=C(C=N1)NC(=O)C2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O

InChI

InChI=1S/C29H29F3N8O.CH4O3S/c1-19-26(38-28-34-9-7-25(37-28)21-4-3-8-33-16-21)15-23(17-35-19)36-27(41)20-5-6-22(24(14-20)29(30,31)32)18-40-12-10-39(2)11-13-40;1-5(2,3)4/h3-9,14-17H,10-13,18H2,1-2H3,(H,36,41)(H,34,37,38);1H3,(H,2,3,4)

InChIKey

ZSASDYCFROUKTJ-UHFFFAOYSA-N

LogP

4.508120000000004

Topological Polar Surface Area

153.54000000000002 Å²

Hydrogen Bond Donor/Acceptor

3 / 12

Complexity

934

Synonyms & References

English

FLUMATINIB MESYLATE [WHO-DD]
HH-GV-678 mesylate
N-(6-methyl-5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)pyridin-3-yl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide mesylate
BenzaMide, 4-[(4-Methyl-1-piperazinyl)Methyl]-N-[6-Methyl-5-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-3-pyridinyl]-3-(trifluoroMethyl)-, MonoMethanesulfonate (9CI)
DTXSID70237780
895519-91-2 (mesylate)
HY-13905
ZSASDYCFROUKTJ-UHFFFAOYSA-N
895519-91-2
95Y8L63NBC
Q27271825
AKOS027422747
FT-0752643
N-(6-methyl-5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)pyridin-3-yl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide methanesulfonate
MS-31003
SCHEMBL4889246
BENZAMIDE, 4-((4-METHYL-1-PIPERAZINYL)METHYL)-N-(6-METHYL-5-((4-(3-PYRIDINYL)-2-PYRIMIDINYL)AMINO)-3-PYRIDINYL)-3-(TRIFLUOROMETHYL)-, METHANESULFONATE (1:1)
N-(6-METHYL-5-{[4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL]AMINO}PYRIDIN-3-YL)-4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-3-(TRIFLUOROMETHYL)BENZAMIDE; METHANESULFONIC ACID
EX-A2059
Flumatinib (mesylate)
BCP08647
CS-1826
HHGV678 mesylate
VKB51991
E73439
CHEMBL3901539
Flumatinib mesylate
BENZAMIDE, 4-((4-METHYL-1-PIPERAZINYL)METHYL)-N-(6-METHYL-5-((4-(3-PYRIDINYL)-2-PYRIMIDINYL)AMINO)-3-PYRIDINYL)-3-(TRIFLUOROMETHYL)-, MONOMETHANESULFONATE
UNII-95Y8L63NBC
methanesulfonic acid;4-[(4-methylpiperazin-1-yl)methyl]-N-[6-methyl-5-[(4-pyridin-3-ylpyrimidin-2-yl)amino]pyridin-3-yl]-3-(trifluoromethyl)benzamide
MFCD28053502

MDL Number

MFCD28053502

FAQ

What regulatory guidelines apply to 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) (CAS: 895519-91-2)?

Regulatory guidelines for 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) (CAS: 895519-91-2) include GHS classification, REACH regulations, and FDA/EPA requirements. Under GHS, it is classified as a hazardous substance due to its potential for causing skin and eye irritation. REACH regulations require manufacturers and importers to register and manage the risks associated with its production and use. FDA and EPA regulations focus on its safety in pharmaceutical and environmental contexts.

Are there alternatives to 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) (CAS: 895519-91-2) in synthesis?

There are alternative reagents and synthetic approaches for 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) (CAS: 895519-91-2). Common alternatives include using different piperazine derivatives or modifying the pyrimidine or pyridine substituents. Isomers or analogs such as 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[3-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide could be considered as alternatives in certain synthetic pathways.

What is the market or research trend for 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) (CAS: 895519-91-2)?

The market and research trends for 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) (CAS: 895519-91-2) are driven by its potential applications in pharmaceuticals, particularly as an analgesic and anticonvulsant. Recent research focuses on its efficacy and safety profiles, leading to increased demand in clinical trials. Market trends indicate a growing interest in developing and optimizing derivatives to enhance these properties.

How should waste containing 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) (CAS: 895519-91-2) be handled?

Waste containing 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) (CAS: 895519-91-2) should be collected and disposed of according to local regulations. Liquid waste should be neutralized and then incinerated or stored in secure, appropriately labeled containers. Professional waste disposal services are recommended to ensure compliance with environmental protection measures. Proper handling includes wearing appropriate personal protective equipment and following safety protocols to prevent exposure and environmental contamination.

Related Compounds

4,4-Difluoro-1-methylpiperidine structure

(1aS,1bS,6bS,7aS,8aS,9R,10S,11S,11aS)-9,10,11-Trihydroxy-10-isopropyl-1b-methyl-1b,3,6,6b,7,7a,9,10,11,11a-decahydrobisoxireno[8a,9:4b,5]phenanthro[1,2-c]furan-4(2H)-one

CAS Number: 147852-78-6

Molecular Formula: C20H26O7

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Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

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4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) | CAS No. 895519-91-2

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Synonyms & References

English

MDL Number

FAQ

What regulatory guidelines apply to 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) (CAS: 895519-91-2)?

Are there alternatives to 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) (CAS: 895519-91-2) in synthesis?

What is the market or research trend for 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) (CAS: 895519-91-2)?

How should waste containing 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) (CAS: 895519-91-2) be handled?

Related Compounds

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