1-(3-Chloro-2,4-difluorophenyl)methanamine

Basic Information

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CAS Number

886761-65-5

Molecular Formula

C7H6ClF2N

Molecular Weight

177.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

220.5±35.0 °C at 760 mmHg

Density

1.4±0.1 g/cm3

Water Solubility

Slightly miscible with water.

Flash Point

87.2±25.9 °C

Refractive Index

1.5195

Vapor Pressure

0.1±0.4 mmHg at 25°C

SMILES

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C1=CC(=C(C(=C1CN)F)Cl)F

InChI

InChI=1S/C7H6ClF2N/c8-6-5(9)2-1-4(3-11)7(6)10/h1-2H,3,11H2

InChIKey

PIIMDRFSWYVCLQ-UHFFFAOYSA-N

LogP

2.0769

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

134

Safety Information

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Hazard Class

Class 8 Class 8

Sensitiveness

Air Sensitive

Synonyms & References

English

EN300-1968051
3-Chloro-2,4-difluorobenzylamine, AldrichCPR
886761-65-5
1-(3-Chloro-2,4-difluorophenyl)methanamine
DS-6152
AKOS015956664
(3-Chloro-2,4-difluorophenyl)methanamine
3-Chloro-2,4-difluorobenzylamine
SCHEMBL1765164
DTXSID50590704
MFCD06660335
JRD-1978

MDL Number

MFCD06660335

FAQ

What regulatory guidelines apply to 1-(3-Chloro-2,4-difluorophenyl)methanamine (CAS: 886761-65-5)?

1-(3-Chloro-2,4-difluorophenyl)methanamine (CAS: 886761-65-5) falls under the classification of hazardous chemicals according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). It is subject to the REACH regulations in the European Union, which require manufacturers and importers to register substances with the European Chemicals Agency. In the United States, it is regulated by the EPA under the Toxic Substances Control Act (TSCA) and the FDA for potential pharmaceutical applications. Proper labeling, storage, and handling are critical to ensure compliance with all relevant regulations.

Are there alternatives to 1-(3-Chloro-2,4-difluorophenyl)methanamine (CAS: 886761-65-5) in synthesis?

Several alternatives to 1-(3-Chloro-2,4-difluorophenyl)methanamine (CAS: 886761-65-5) exist in synthesis. For instance, 1-(3-bromo-2,4-difluorophenyl)methanamine can be used as a bromo derivative. Other options include 1-(3-iodo-2,4-difluorophenyl)methanamine and 1-(3-methoxy-2,4-difluorophenyl)methanamine. These alternatives offer similar functionality but with different functional groups, providing flexibility in synthetic routes.

What is the market or research trend for 1-(3-Chloro-2,4-difluorophenyl)methanamine (CAS: 886761-65-5)?

The market for 1-(3-Chloro-2,4-difluorophenyl)methanamine (CAS: 886761-65-5) is currently driven by its use in the pharmaceutical and chemical industries. Research trends suggest an increasing focus on its application in medicinal chemistry, particularly in the synthesis of new drugs. The compound's unique chemical structure makes it a valuable tool in the development of novel pharmaceuticals. Additionally, there is growing interest in its use as a precursor in organic synthesis, with ongoing studies exploring its potential in various chemical transformations.

How should waste containing 1-(3-Chloro-2,4-difluorophenyl)methanamine (CAS: 886761-65-5) be handled?

Waste containing 1-(3-Chloro-2,4-difluorophenyl)methanamine (CAS: 886761-65-5) should be managed with care to minimize environmental impact. Collection of waste should be done in appropriate containers, and it is advisable to neutralize or inactivate the compound before disposal. Incineration is a common method for disposal, provided it is conducted in an adequately controlled incinerator. Professional waste disposal services are recommended to ensure compliance with local regulations. Environmental protection measures, such as proper containment and handling, are crucial to prevent accidental spills or releases into the environment.