(8-Methylimidazo[1,2-a]pyridin-2-yl)methanol

Basic Information

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CAS Number

872362-98-6

Molecular Formula

C9H10N2O

Molecular Weight

162.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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CC1=CC=CN2C1=NC(=C2)CO

InChI

InChI=1S/C9H10N2O/c1-7-3-2-4-11-5-8(6-12)10-9(7)11/h2-5,12H,6H2,1H3

InChIKey

USLQEDJXTXXZAC-UHFFFAOYSA-N

LogP

1.13502

Topological Polar Surface Area

37.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

163

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

MFCD08752621
AKOS009590097
AM804455
{8-methylimidazo[1,2-a]pyridin-2-yl}methanol
XJB36298
SB39244
DTXSID20599426
(8-Methyl-imidazo[1,2-a]pyridin-2-yl)-methanol
SCHEMBL103671
(8-Methylimidazo[1,2-a]pyridin-2-yl)methanol
AS-66252
CS-0035990
FT-0737312
872362-98-6
(8-Methylimidazo[1,2-a]pyridin-2-yl)methanol, AldrichCPR
(8-Methyl-Imidazo[1,2-A]Pyridin-2-YL)-Methanol
(8-methyl-imidazo[1,2-a]pyridin-2-yl)methanol

MDL Number

MFCD08752621

Customs Code

2933990090

FAQ

What are the physical and chemical properties of (8-Methylimidazo[1,2-a]pyridin-2-yl)methanol (CAS: 872362-98-6)?

(8-Methylimidazo[1,2-a]pyridin-2-yl)methanol is a solid with a crystalline form. It has a molecular weight of approximately 228.24 g/mol. The compound is poorly soluble in water but more soluble in organic solvents like methanol and ethanol. It is known for its stability in air and is relatively non-reactive under normal conditions. It is used in research applications and chemical synthesis.

How is (8-Methylimidazo[1,2-a]pyridin-2-yl)methanol (CAS: 872362-98-6) typically synthesized?

(8-Methylimidazo[1,2-a]pyridin-2-yl)methanol can be synthesized through a multistep process involving the condensation of an appropriate imidazopyridine derivative with methanol in the presence of a catalytic amount of a strong acid like sulfuric acid. The yield is typically around 70-80%, and the reaction is carried out under mild conditions to ensure selectivity.

What industries use (8-Methylimidazo[1,2-a]pyridin-2-yl)methanol (CAS: 872362-98-6)?

(8-Methylimidazo[1,2-a]pyridin-2-yl)methanol is primarily used in the pharmaceutical industry for the development of novel compounds with potential biological activities. It also finds applications in the semiconductor industry as an intermediate for the synthesis of other materials. It is less common in polymer and sensor applications.

What precautions should be taken when handling (8-Methylimidazo[1,2-a]pyridin-2-yl)methanol (CAS: 872362-98-6)?

When handling (8-Methylimidazo[1,2-a]pyridin-2-yl)methanol, it is recommended to wear appropriate personal protective equipment (PPE), including gloves and safety glasses. Handle in a fume hood to minimize exposure. In case of a spill, use appropriate absorbent materials and dispose of them according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.