N-{2-[(3S)-3-({4-Hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl}amino)-1-pyrrolidinyl]-2-oxoethyl}-3-(trifluoromethyl)benzamide | CAS No. 857679-55-1

N-{2-[(3S)-3-({4-Hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl}amino)-1-pyrrolidinyl]-2-oxoethyl}-3-(trifluoromethyl)benzamide

Basic Information

CAS Number

857679-55-1

Molecular Formula

C29H31F3N6O3

Molecular Weight

568.6 g/mol

AD

Basic Physical Properties

Density

1.40

O=C(N4CC[C@H](NC3CCC(O)(c2ncc(c1ncccn1)cc2)CC3)C4)CNC(=O)c5cccc(c5)C(F)(F)F

InChI

InChI=1S/C29H31F3N6O3/c30-29(31,32)21-4-1-3-19(15-21)27(40)36-17-25(39)38-14-9-23(18-38)37-22-7-10-28(41,11-8-22)24-6-5-20(16-35-24)26-33-12-2-13-34-26/h1-6,12-13,15-16,22-23,37,41H,7-11,14,17-18H2,(H,36,40)/t22?,23-,28?/m0/s1

InChIKey

ZNSVOHSYDRPBGI-CBQRAPNFSA-N

LogP

3.3081000000000014

Topological Polar Surface Area

120.34 Ų

Hydrogen Bond Donor/Acceptor

3 / 9

Synonyms & References

English

  • INCB8761(PF-4136309)
  • INCB8761
  • N-{2-[(3S)-3-({4-Hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohe xyl}amino)-1-pyrrolidinyl]-2-oxoethyl}-3-(trifluoromethyl)benzami de

MDL Number

MFCD22419015

FAQ

What regulatory guidelines apply to N-{2-[(3S)-3-({4-Hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl}amino)-1-pyrrolidinyl]-2-oxoethyl}-3-(trifluoromethyl)benzamide (CAS: 857679-55-1)?

N-{2-[(3S)-3-({4-Hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl}amino)-1-pyrrolidinyl]-2-oxoethyl}-3-(trifluoromethyl)benzamide (CAS: 857679-55-1) is subject to various regulatory guidelines including GHS classification for hazardous materials, REACH regulations for chemical safety, and FDA/EPA guidelines for pharmaceutical and environmental safety. Compliance with these regulations is crucial for the production, handling, and disposal of this compound.

Are there alternatives to N-{2-[(3S)-3-({4-Hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl}amino)-1-pyrrolidinyl]-2-oxoethyl}-3-(trifluoromethyl)benzamide (CAS: 857679-55-1) in synthesis?

There are several alternatives to N-{2-[(3S)-3-({4-Hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl}amino)-1-pyrrolidinyl]-2-oxoethyl}-3-(trifluoromethyl)benzamide (CAS: 857679-55-1) in synthesis, such as other pyrimidinyl-pyridinyl derivatives or related amides. These alternatives can provide similar functionalities but with different structural characteristics, which may offer different synthetic pathways and properties.

What is the market or research trend for N-{2-[(3S)-3-({4-Hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl}amino)-1-pyrrolidinyl]-2-oxoethyl}-3-(trifluoromethyl)benzamide (CAS: 857679-55-1)?

The market for N-{2-[(3S)-3-({4-Hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl}amino)-1-pyrrolidinyl]-2-oxoethyl}-3-(trifluoromethyl)benzamide (CAS: 857679-55-1) is evolving with increasing demand in pharmaceutical and research applications. Research trends focus on its potential in drug discovery and development, particularly in oncology and other therapeutic areas. The compound's unique chemical structure continues to attract interest from researchers.

How should waste containing N-{2-[(3S)-3-({4-Hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl}amino)-1-pyrrolidinyl]-2-oxoethyl}-3-(trifluoromethyl)benzamide (CAS: 857679-55-1) be handled?

Waste containing N-{2-[(3S)-3-({4-Hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl}amino)-1-pyrrolidinyl]-2-oxoethyl}-3-(trifluoromethyl)benzamide (CAS: 857679-55-1) should be collected in appropriate containers and disposed of through professional waste disposal services. Proper incineration or chemical treatment is recommended to ensure compliance with environmental regulations and safety standards. Handling should be conducted in a well-ventilated area, and all necessary personal protective equipment should be worn to prevent exposure and ensure safety.

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